For those who are saying all of the benefits disappear after a certain amount of time, that was starting to happen with my son but it was because he was growing and needed the dose adjusted. Now we're back on track.

My son showed immediate differences after receiving b12 shots (like 2 hours). But after about 6 months of treatment, all benefits disapeared.

We started B12 injections for all three kiddos. My daughters vocalizations have greatly improved and my oldest sons desire for socialization and tolerance improved. My other son didn't show any change. The two that did respond , did so after about 3 injections (given every three days). The suspense must be killing you but I don't know if there is a really good answer for you. Hope this helps:)

She's now been on the shots for about 5 weeks now, as well as some new supplements (GABA, folinic acid, etc). We also started HBOT last week. She's doing great! I would still consider her largely nonverbal though the number of actual words she says is increasing. She is waaaaay more connected and engaged with everybody. She plays so appropriately with toys and I think her physical strength and coordination are improving too (she is hypotonic). It's hard to say if its B12 that's doing it or one of the other many things we're doing. I'm a scientist so that aspect bugs me LOL but as a mom, I don't really care as long as its working!!!!!

Do it. We're about 15 shots in and I'm kicking myself for not doing it years ago when I first learned about it. It can't hurt to try and the benefits could be amazing!